How Oxygenation In Your Blood Is Measured?

Yesterday we talked about Red Blood Cells (RBC) or erythrocytes and hemoglobin thus we now know that hemoglobin plays a big role in oxygenation of all cells in our body. In relation to that, we will talk about oximeter today. What is an oximeter? Oximeter is an instrument use to measure oxygen percentage in hemoglobin or simply the oxygenation of the blood.

How oxygen percentage in hemoglobin is measured? Oximeters are usually attached on fingertip or at the earlobe of patient. Then, absorption and saturation of hemoglobin in patient’s blood are recorded using oxymeter’s probe at 650nm-805nm range of wavelength of light.  Please take note that oximeter just measure oxygenation and not oxygen metabolism.

Like any other instruments, there are factors that could cause problem in readings of pulse oximeter, slow blood flow due to venous congestion or vasoconstriction is a great example for it. There are lots of hemoglobin types, 2 of the said types are oxyhemoglobin and carboxyhemoglobin (methemoglobin). Carboxyhemoglobin (methemoglobin) can be confused as oxyhemoglobin by pulse oximeter because these two types of hemoglobin are difficult to distinguish. Bright overhead lights and nail varnish could also cause false reading thus, it should be avoided.

Pulse oximeter is not solely for hospital use with a purpose of detecting oxygen related problems and in analyzing if it is necessary for the patient to undergo an oxygen therapy. Mountain climbers,  and people who undergo vigorous exercise like professional athletes uses portable pulse oximeter to measure their pulse rate and oxygenation of the blood too. People who are dependent on supplemental oxygen like pilot flying in non-pressurized airplanes use this instrument to measure the amount of supplemental oxygen needed.

We all know that oxygen is also a form of medication, this kind of medication could not be given without first determining the oxygen level in our blood. That is how important oximeter is to our community.

Know More About Your Red Blood Cells

Know More About Your Red Blood Cells

My friend Lilia has her own car now. It is one of her dreams to have one and finally her dream come true. She said she need to have even a cheap car insurance for her car now thus, she get quotes from car insurances online. Talking about cars, our Red Blood Cells (RBC) or erythrocytes acts as cars in the body too.

Through circulatory system, Red Blood Cells (RBC) or erythrocytes take up oxygen from the lungs and deliver the oxygen to millions of cells in our body. From our cells, it carries the carbon dioxide back to the lungs for excretion. It only take about 20 seconds for Red Blood Cells (RBC) or erythrocytes to circulate within our body, isn’t that a great fact? They could be compared to fast cars with great purpose . They should not be caught by any kind of traffic jam or accident or else our body will suffer.

In normal adult, women has 4-5 million of Red Blood Cells (RBC) or erythrocytes in every microliter of blood while men have 5-6 million of Red Blood Cells (RBC) or erythrocytes per microliter of blood. And, for every Red Blood Cell (RBC) or erythrocyte it  contains about 270 million of hemoglobin biomolecules. Hemoglobin contain iron that is responsible for the red color of our blood and protein that transports oxygen to cells of our body.

Lack of hemoglobin is called anemia. With anemia, no enough transport system for oxygen to be carried to the cells thus person may suffer from shortness of breath, chest pain, headache, dizziness, and feeling tired and weak. There is paleness in skin too. And, if anemia will take so long, complication may take place like arrhythmia that could damage the heart.

Like cheap car insurance for your car, we need cheap but nutritious food to ensure our red cells for them to function well. Foods that are rich in iron, vitamin C and other nutrients that could keep our Red Blood Cells (RBC) or erythrocytes healthy for them to function well. Fresh fruits and vegetables are great for our Red Blood Cells (RBC) or erythrocytes.

Iron Supplements and Iron Deficiency Anemia

You and your family are taking iron supplements? Did you know that too much iron in your body is harmful? Yes, our body needs iron, it is important for red blood cell production but too much of it is harmful to the body. There is a theory that extra stored iron in your body release harmful free radicals that may put you to risk for heart problems, liver damage, cancer,iron overdose in children and other illnesses. Medically speaking when there is an excessive amount of iron accumulated in the blood and tissues is is called hemosiderosis if the accumulated iron in the macrophages causes parenchymal cell injury. If the extra iron accumulates in the parenchymal cells and injures the tissue it is called hemochromatosis.

Because of iron side effects, most doctors agree that it is not necessary to take iron supplements unless your blood test shows that you need it. If the person is anemic, with low hemoglobin and, or hematocrit level in the blood, it does not mean automatically that he is suffering from iron deficiency and need to take iron supplements, always bear in mind that anemia has lots of causes and iron deficiency is just one of them. To confirm that the person is suffering from iron deficiency, the person will undergo a special laboratory test called serum ferritin test.

Again, taking iron supplements are not recommended unless prescribed by your doctor. If you want to make sure that your family family is getting enough iron for their body needsgo for good food sources of iron. Fish, poultry, red meat, shellfish, tofu, potatos, peas, beans, pumpkin seeds and dried apricots are rich in iron, some cereals and other processed foods are fortified with iron too thus, you need not to take iron supplements unless prescribed by your physician.

Poisons in Tobacco Smoke

Poisons in Tobacco Smoke

Poisonous? Consider tobacco smoke  as one. It contain lots of toxic substances that is threatening not just to the smokers but to your family health as well. Did you know that tobacco smoke contains more than 4,000 chemicals including 200 poisonous and 40 carcinogenic compounds? It causes more than 40 diseases. No wonder, World Health Organization statistics showed that nearly 1 0f every 5 death nowadays are related to smoking. One in every seven seconds die from tobacco-related illness. It is due to either mainstream tobacco smoking or through passive (involuntary) smoking.

Here are some of the carcinogenic compounds you can find on tobacco smoke:

4-Aminobiphenyl
-It is confirmed to cause cancer in humans. Bladder, lung, colon, and breast cancers have been associated with 4-ABP.

-The worst thing about 4-ABP is it can cross the placenta & render child susceptible to bladder cancer.

Arsenic
-Inorganic arsenic is present in tobacco smoke and has been linked to lung, skin, bladder, liver, kidney and prostate cancers.

Benzene
-Study showed that high levels of benzene may cause low birth weights, delayed bone formation and bone marrow damage in animals.

-Benzene is highly toxic. Inhalation of extremely high levels of benzene may cause rapid heart rate, confusion, tremors, drowsiness, dizziness, headache, unconsciousness or even death.

-All three blood cell lines may be unfavorably affected by long term exposure to benzene. Low white blood cells or leucopenia, low red blood cells or anemia and low platelet count or thrombocytopenia may exist in varying degree. In case where there is a reduction in all three blood cell lines it is already called pancytopenia, this may happen due toxicity from long term exposure to benzene from tobacco smoking.

-Chronic exposure to benzene through tobacco smoke may also lead to increase risk of acquiring leukemia and, in many cases, is preceded by aplastic anemia.

Cadmium
-Cadmium is a toxic heavy metal pollutant that can be found in tobacco smoke. Tobacco smoke is an important source of air cadmium because tobacco leaves naturally accumulate and concentrate quite high levels of cadmium.

- An average cigarette contains approximately 1.05 micrograms/g of cadmium in cigarette with filter tip and approximately 1.61 micrograms/g in regular cigarette. And, about 10% of the cadmium content in cigarette is inhaled when it is smoked.

-Exposure to high levels of cadmium may lead to high blood pressure, anemia and renal failure, lung and, or liver damage.

-It is also considered as possible carcinogen.

Chromium
-As you inhale air containing chromium, like in tobacco smoke, chromium enters your body. Did you know that some forms of chromium can remain in the lungs for several years or longer?

-When you breathe air containing chromium, some of the chromium will enter your body through your lungs. Some forms of chromium can remain in the lungs for several years or longer.

-The International Agency for Research on Cancer (IARC) has determined that chromium (VI) compounds are carcinogenic to humans. The National Toxicology Program 11th Report on Carcinogens classifies chromium (VI) compounds as known to be human carcinogens. Inhalation of chromium has been shown to cause lung cancer.

-It can cause respiratory problems, depressed immune system- resulting to a lower ability to fight disease, birth defects and other developmental problem, infertility and tumor formation.

2-Naphthylamine
-It can cause bladder cancer.

N-Nitrosodiethylamine
-It can induce benign and malignant tumors in respiratory, upper digestive tracts, liver and kidneys.

N-Nitrosopyrrolidine
-It can produce hepatocellular carcinomas, one of the top in leading liver cancer death type worldwide.

N-Nitrosodiethanolamine
-It is connected to esophageal cancer.

Nickel
-The International Agency for Research on Cancer (IARC) has determined that some nickel compounds are carcinogenic to humans.

-More nickel is absorbed from the lungs into the body when nickel particles readily dissolve in water. If it does not easily dissolved in water, like chromium, nickel particles may remain in the lungs for a long time, and can only be excreted from lungs through coughing out or swallowing the mucus.

-Unborn child can be exposed to nickel through maternal blood supply to fetus.

-Babies are exposed to nickels through breastmilk of mother who is exposed to nickel and through passive tobacco smoking.

-It causes reduced lung function, chronic bronchitis, and cancer of the lung and nasal sinus

Lead-210 and Polonium-210 (Radon)
-Did you know that tobacco leaves used in making cigarettes contain radioactive materials? Yes, lead-210 and polonium-210 are radioactive materials.

- Lead-210 and polonium-210 are toxic radioactive heavy metals. They build up over time in delicate lung tissue and are a key risk factor for lung cancer. How? Tar from tobacco smoke builds up in the bronchioles; accumulated tar traps lead-210 and polonium-210 against the tissues of the bronchioles. Most of what is deposited in the bronchioles is lead-210 which has a half life of 22.3 years; eventually it decays and become dominant radionuclide. On the other hand, polonium-210 has only half life of 138 days but it quickly increases in concentration, thus, over the time, as its concentration rises, an intense localized radiation doses may occur in the bronchioles.

-Researchers believe that lead-210 and polonium-210 in tobacco smoke are significant factors for lung cancer in smokers.

Vinyl Chloride
-Inhalation of high levels of vinyl chloride may cause dizziness, drowsiness or even death.

-Chronic exposure to vinyl chloride may cause severe nerve damage and immune reactions.

-The World Health Organization has determined that vinyl chloride is a human carcinogen.

-Vinyl chloride, has also been shown to have an effect on human reproductive system.